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Natural Hangover Relief Supplement

New Thinking

Most of us enjoy having a few drinks with friends, but that morning-after feeling offers a painful reminder that alcohol is a significant toxin!

If, like many people, you think the dehydrating effects of alcohol are to blame for your hangover symptoms, it's time to meet Doctor Nima Alavi, an Australian pharmacist who is changing the way we think about hangovers.

According to Dr. Alavi, “dehydration is actually only a very small part of why we wake up feeling so awful after a fun night [while] the real reason you get a hangover is actually directly related to how alcohol is broken down in your body.”

What Causes Hangover Symptoms?

What Dr. Alavi and fellow researchers have discovered is that the main culprit for hangover symptoms appears to be acetaldehyde (AcH), a highly toxic compound that builds up in your blood overnight as your body breaks down alcohol.

After a night of drinking, the elevated level of AcH in your blood, in addition to simple dehydration, can cause hangover symptoms such as:

  • Increased sweating
  • Increased heart and respiration rate
  • Dry mouth or throat
  • Nausea and vomiting
  • Headache (Eriksson, 2001.)

AcH is a highly reactive substance, causing significant oxidative damage to organs and tissues including the liver and brain (McCarty, 2013). As such, taking steps to enhance antioxidant levels and improve the breakdown of AcH could help decrease the short-term negative effects of alcohol.

Meet HangoverX

Recognizing that most hangover products are simply souped-up rehydration formulas, Dr. Alavi set out to create an innovative new product that targets the root causes of hangover symptoms.

HangoverX is designed to be taken before or shortly after consuming alcohol so as to help keep AcH levels in check. This supplement contains antioxidants and co-factors for the conversion of AcH to less damaging acetate, including vitamins B1, B2, B3, B6 and B12, vitamin C and an array of herbs traditionally used to support liver and digestive function.

Vital Nutrients for Alcohol Metabolism

To break down AcH, your body needs specific nutrients such as vitamin B3 (niacin). The irony, though, is that alcohol inhibits the absorption of many nutrients, especially B vitamins, which are essential for proper nervous system function and digestion, as well as for healthy energy metabolism (Catazaro & Brecher, 2013).

As alcohol depletes B vitamins, with AcH seen to bind specifically to vitamin B1 (thiamine) and vitamin B6 (pyridoxine), it is not surprising that a hangover can leave you feeling sluggish and unable to focus.

To counteract this negative effect of alcohol, HangoverX was formulated with meaningful amounts of key B vitamins, alongside 150 mg of vitamin C (as calcium ascorbate) to provide key antioxidant protection against alcohol-related free radicals that can damage your organs and tissues.

Herbal Support for Hangover Relief

HangoverX also provides 120 mg of milk thistle (Silybum marianum), an herb traditionally used to support liver function and normal detoxification processes. The active flavonoid complex, silymarin, found in milk thistle has a protective antioxidant effect and supports the body's natural detoxification processes (National Cancer Institute, 2016).

Milk thistle has even been shown to inhibit the formation of leukotrienes, substances that can cause damage to the liver (Pradhan et al., 2006), while increasing levels of glutathione (GSH) and superoxide dismutase (SOD) (Pradhan et al., 2006). These key antioxidant enzymes are typically depleted by alcohol, leaving the body vulnerable to free radical attack; by enhancing GSH and SOD, milk thistle can help guard against oxidative damage associated with AcH enzymes (Wang et al., 2016).

As milk thistle can affect the metabolism of certain drugs, it is important to talk to your physician prior to taking any supplements containing this herb.

Dandelion and Ginger

Dandelion (Taraxacum officinale) root extract is included in HangoverX for its supportive effect on digestive and detoxification processes. Dandelion has antioxidant activity and is traditionally used to support bile flow, which helps the body eliminate toxins (Schütz et al., 2006; You et al., 2010).

HangoverX also contains ginger, an herb commonly used to support digestive function and help quell feelings of nausea, a common symptom of a hangover (Marx et al., 2015). One of ginger’s major active constituents, 6-Gingerol, is a free radical-scavenging compound that supports normal levels of protective antioxidant enzymes SOD and GSH (Wang et al., 2016).

The Secret Weapon Against Hangovers - Bacopa monnieri

Bacopa monnieri, commonly known as the 'herb of grace,' is unfamiliar to many people, but is highly regarded in Ayurvedic medicine as a supportive herb for healthy cognitive function and memory throughout life.

In recent years, scientific research has found that B. monnieri contains bioactive compounds including flavonoids and triterpines such as beta-sitosterol (Ramasamy et al., 2015). While acetaldehyde can have adverse effects on an area of the brain called the hippocampus (resulting in impaired memory function associated with alcohol intoxication), the compounds in B. monnieri may exert a protective effect on the hippocampus, helping to support normal cognitive processes (Tokuda et al., 2013; Roodenrys et al., 2002).

Natural Hangover Support from HangoverX!

Natural remedies intended to alleviate hangover symptoms have been used for centuries, but it is only recently that scientists such as Dr. Alavi have started to uncover the true potential of these herbs and nutrients, including their antioxidant activity and support for normal detoxification processes.

As always, moderating alcohol consumption is the best way to prevent a hangover, but if you’re looking for a little natural support after a big night out, try HangoverX - It’s 100% natural, gluten-free, sugar-free and lactose-free. Simply take the recommended amount of capsules with water before bed.

Experience the benefits of HangoverX for yourself by ordering your first bottle today.

Shop HANGOVERX now.  

Each capsule of HangoverX contains: Cyanocobalamin 50mcg, Nicotinamide 50mg, Thiamine nitrate 15mg, Riboflavin 15mg, pyridoxine hydrochloride 10g, Calcium ascorbate 150mg. Herbal Equivalent to dry: Silybum marianum fruit dry 120mg, Taraxacum officinale root dry 120mg, Zingiber officinale rhizome fresh 150mg, Bacopa monnieri whole plant 250g.

 

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

HangoverX does not affect blood alcohol levels. Always drink responsibly.

 

References

Catazaro JR, & Brecher AS. (2013). The influence of B-complex vitamins upon the prolongation of prothrombin time by acetaldehyde. Blood Coagul Fibrinolysis, Jul;24(5):477-83.

Eriksson CJ. (2001). The role of acetaldehyde in the actions of alcohol (update 2000). Alcohol Clin Exp Res, May;25(5 Suppl ISBRA):15S-32S.

Ladas EJ, Kroll DJ, Oberlies NH, et al. (2010). A randomized, controlled, double-blind, pilot study of milk thistle for the treatment of hepatotoxicity in childhood acute lymphoblastic leukemia (ALL). Cancer, 116:  506–513.

Marx W, Kiss N, Isenring L. (2015). Is ginger beneficial for nausea and vomiting? An update of the literature. Curr Opin Support Palliat Care, Jun;9(2):189-95.

McCarty MF. (2013). Nutraceutical strategies for ameliorating the toxic effects of alcohol. Med Hypotheses, Apr;80(4):456-62.

National Cancer Institute (NCI). Milk Thistle (PDQ®), http://www.cancer.gov/cancertopics/pdq/cam/milkthistle/HealthProfessional.  Accessed 02/27/16.

Pradhan SC, Girish C. et al. (2006). Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine. Indian J Med Res. Nov;124(5):491-504.

Ramasamy S, Chin SP, Sukumaran SD, et al. (2015). In Silico and In Vitro Analysis of Bacoside A Aglycones and Its Derivatives as the Constituents Responsible for the Cognitive Effects of Bacopa monnieri. PLoS One, May 12;10(5):e0126565.

Roodenrys S, Booth D, Bulzomi S, et al. (2002). Chronic effects of Brahmi (Bacopa monnieri) on human memory. Neuropsychopharmacology, 27(2):279-281.

Schütz K, Carle R, Schieber A. (2006). Taraxacum--a review on its phytochemical and pharmacological profile. J Ethnopharmacol, Oct 11;107(3):313-23.

Ströhle A, Wolters M, Hahn A. (2012). Alcohol intake--a two-edged sword. Part 1: metabolism and pathogenic effects of alcohol. Med Monatsschr Pharm, Aug;35(8):281-92; quiz 293-4.

Tokuda K, Izumi Y, Zorumski CF. (2013). Locally-generated Acetaldehyde Contributes to the Effects of Ethanol on Neurosteroids and LTP in the Hippocampus. Neurol Clin Neurosci, Jul;1(4):138-147.

Wang F, Li Y, Zhang YJ, Zhou Y, Li S, Li HB. (2016). Natural Products for the Prevention and Treatment of Hangover and Alcohol Use Disorder. Molecules, Jan 7;21(1). pii: E64.

You Y, Yoo S, Yoon HG, et al. (2010). In vitro and in vivo hepatoprotective effects of the aqueous extract from Taraxacum officinale (dandelion) root against alcohol-induced oxidative stress. Food Chem Toxicol, 48(6):1632-7.